Our Environmental, Social and Governance (ESG) Initiatives
At PureTech, our commitment to sustainability, through strong Environmental, Social and Governance (ESG) practices, remains steadfast. Our core priority is innovating to create new classes of medicine which transform the lives of patients, and we recognize that ESG plays an important role in supporting our achievement of this goal.
Our ESG Approach
PureTech’s ESG framework is built around three strategic areas of focus to meet the needs of our stakeholders and to achieve a positive social impact: Patients, People and Planet. Our approach is underpinned by our robust governance framework, which helps us to deliver our mission, strategy and purpose in a consistent and responsible way.

Patients
29
therapeutics and therapeutic candidates generated from PureTech’s R&D engine
3
therapeutics taken from inception at PureTech to FDA approval
80%
of clinical trials were successful1
People
44%
gender diversity on Leadership level
Continue to exceed FTSE Women Leaders 40% women in leadership recommendation2
43%
gender diversity on Board level3
Continue to exceed FTSE Women Leaders 40% women in leadership recommendation2
43%
ethnic diversity on Board level3,4
Continue to exceed Parker Review's "One by 2024" target
Planet
14%
less energy consumed
at the Boston HQ compared to the 2030 Challenge baseline
66%
fewer GHG emissions
generated at the Boston HQ compared to the 2030 Challenge baseline
Our Governance Structure
Our ESG Committee was founded in 2020 and is chaired by non-Executive Director, Kiran Mazumdar-Shaw. The ESG committee is responsible for managing, reviewing and advancing our ESG progress and enhancing disclosure and transparency through our annual ESG reporting process. The ESG committee is composed of a non-Executive Director and supported by at least one C-Suite Officer, and reports directly to the Board. The work of the ESG Committee is supported by a dedicated internal working group, that is responsible for the implementation of strategy and welcomes active engagement with shareholders and other stakeholders on matters relating to ESG and corporate stewardship.

Our Reporting Frameworks
In April 2025, we published the 5th edition of our ESG report (see report here) detailing our ESG strategy, performance and ongoing progress. This report was developed based on feedback from our stakeholders and metrics used by corporate responsibility and sustainability rating providers. In 2024, we continued to enhance our disclosures and transparency by aligning our reporting with best practice frameworks including: Sustainability Accounting Standards Board (SASB), United Nations Sustainable Development Goals (SDGs), and the Task Force on Climate-related Financial Disclosures (TCFD) framework.
Our ESG Performance
PureTech participates in various third party ESG Risk Ratings to evaluate our exposure to material industry-specific ESG risks. The assessment process and its results guide our ESG program with a goal to improve our initiatives each year. In 2024, we participated in and received positive ratings from — Received positive ESG ratings from CDP, FTSE Russell, ISS, Sustainalytics, and S&P Global. This reflects our commitment and continuous efforts to contribute to a sustainable future.

1 The percentage includes number of successful trials out of all trials run for all therapeutic candidates advanced through at least Phase 1 by PureTech or its Founded Entities from 2009 onward.
2 FTSE Women Leaders Review has set 40% women on both Board and in leadership (defined as the Executive Committee and Direct Reports combined) target.
3 Board composition as of December 31, 2024.
4 Three out of seven directors were from an ethnic minority background on the Board as of December 31, 2024.
Note: FTSE Russell (the trading name of FTSE International Limited and Frank Russell Company) confirms that PureTech Health has been independently assessed according to the FTSE4Good criteria, and has satisfied the requirements to become a constituent of the FTSE4Good Index Series. Created by the global index provider FTSE Russell, the FTSE4Good Index Series is designed to measure the performance of companies demonstrating strong Environmental, Social and Governance (ESG) practices. The FTSE4Good indices are used by a wide variety of market participants to create and assess responsible investment funds and other products.









